Respiratory System

Nose, Septum - Perforation

    Narrative
    Nose, Septum - Perforation in a female B6C3F1/N mouse from a chronic study. A perforation is present in the nasal septum (arrow).
    Nose, Septum - Perforation in a female B6C3F1/N mouse from a chronic study. A perforation is present in the nasal septum (arrow).
    Nose, Septum - Perforation in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). Squamous metaplasia of the respiratory epithelium (arrow) is adjacent to the perforation.
    Nose, Septum - Perforation in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). Squamous metaplasia of the respiratory epithelium (arrow) is adjacent to the perforation.

    Authors

    Rodney A. Miller, DVM, PhD, DACVP
    NC Pathology Group Manager
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Reviewers

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Ronald Herbert, DVM, PhD
    NTP Pathologist
    Group Leader, Pathology Support Group
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC