Alimentary System

Salivary Gland, Parotid - Basophilic Hypertrophic Focus

    Narrative
    Salivary gland, Parotid - Basophilic hypertrophic focus in a female F344/N rat from a chronic study. A focus of hypertrophied cells with increased basophilia is present (arrow).
    Salivary gland, Parotid - Basophilic hypertrophic focus in a female F344/N rat from a chronic study. A focus of hypertrophied cells with increased basophilia is present (arrow).
    Salivary gland, Parotid - Basophilic hypertrophic focus in a female F344/N rat from a chronic study (higher magnification of Figure 1). A focus of hypertrophied cells with increased basophilia is present (arrow).
    Salivary gland, Parotid - Basophilic hypertrophic focus in a female F344/N rat from a chronic study (higher magnification of Figure 1). A focus of hypertrophied cells with increased basophilia is present (arrow).
    Salivary gland, Parotid - Basophilic hypertrophic focus in a male F344/N rat from a chronic study. Multiple foci of hypertrophied cells with increased basophilia are present (arrows).
    Salivary gland, Parotid - Basophilic hypertrophic focus in a male F344/N rat from a chronic study. Multiple foci of hypertrophied cells with increased basophilia are present (arrows).
    Salivary gland, Parotid - Basophilic hypertrophic focus in a female F344/N rat from a chronic study. Multiple foci of hypertrophied cells with increased basophilia are present (arrows).
    Salivary gland, Parotid - Basophilic hypertrophic focus in a female F344/N rat from a chronic study. Multiple foci of hypertrophied cells with increased basophilia are present (arrows).
    Salivary gland, Parotid - Basophilic hypertrophic focus in a male F344/N rat from a subchronic study (higher magnification of Figure 4). Multiple foci of hypertrophied cells with increased basophilia are present (arrows).
    Salivary gland, Parotid - Basophilic hypertrophic focus in a male F344/N rat from a subchronic study (higher magnification of Figure 4). Multiple foci of hypertrophied cells with increased basophilia are present (arrows).

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC