Respiratory System

Lung - Pigment

    Narrative
    Lung, Alveolus - Pigment in a female Harlan Sprague-Dawley rat from a chronic study. The pigment is most likely hemosiderin and is contained within macrophages.
    Lung, Alveolus - Pigment in a female Harlan Sprague-Dawley rat from a chronic study. The pigment is most likely hemosiderin and is contained within macrophages.
    Lung - Pigment in a male F344/N rat from a chronic study. The golden brown pigment is most likely hemosiderin secondary to hemorrhage associated with acute inflammation.
    Lung - Pigment in a male F344/N rat from a chronic study. The golden brown pigment is most likely hemosiderin secondary to hemorrhage associated with acute inflammation.

    Authors

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist/NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Darlene Dixon, DVM, PhD, DACVP
    Group Leader
    Molecular Pathogenesis Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Ronald A. Herbert, DVM, PhD
    Group Leader/NTP Pathologist
    Pathology Support Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Lauren M. Staska, DVM, PhD, DACVP
    Senior Pathologist
    WIL Research
    Hillsborough, NC

    Reviewers

    Gary A. Boorman, DVM, PhD, DACVP, DABT, DACLAM
    Pathologist
    Covance Laboratories, Inc.
    Chantilly, VA

    Robert C. Sills, DVM, PhD, FIATP
    Chief, Cellular and Molecular Pathology Branch
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC