Endocrine System

Thyroid Gland, Follicle - Dilation

    Narrative
    Thyroid gland, Follicle - Dilation in a male B6C3F1 mouse from a chronic study. There is a single dilated follicle (arrow).
    Thyroid gland, Follicle - Dilation in a male B6C3F1 mouse from a chronic study. There is a single dilated follicle (arrow).
    Thyroid gland, Follicle - Dilation in a male B6C3F1 mouse from a chronic study. This higher magnification of Figure 1 shows the flattened epithelium lining the dilated follicle.
    Thyroid gland, Follicle - Dilation in a male B6C3F1 mouse from a chronic study. This higher magnification of Figure 1 shows the flattened epithelium lining the dilated follicle.
    Thyroid gland, Follicle - Dilation in a male F344/N rat from a chronic study. There is dilation of several adjacent follicles.
    Thyroid gland, Follicle - Dilation in a male F344/N rat from a chronic study. There is dilation of several adjacent follicles.
    Thyroid gland, Follicle - Dilation in a male F344/N rat from a chronic study. Higher magnification of Figure 3 shows the flattened epithelium of the dilated follicles and pigmented macrophages in one of the follicles (arrow).
    Thyroid gland, Follicle - Dilation in a male F344/N rat from a chronic study. Higher magnification of Figure 3 shows the flattened epithelium of the dilated follicles and pigmented macrophages in one of the follicles (arrow).

    Authors

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Thomas J. Rosol, DVM, PhD, DACVP
    Professor of Veterinary Biosciences
    Senior Advisor, Life Sciences, Technology Commercialization and Knowledge Transfer
    The Ohio State University
    Columbus, OH

    Susan A. Elmore, MS, DVM, DACVP, DABT, FIATP
    Staff Scientist, NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC