Hematopoietic System

Bone Marrow - Infiltration Cellular, Histiocyte

    Narrative
    Bone marrow in a female F344/N rat from a 2-year study. Increased numbers of pale-staining vacuolated histiocytes (arrows) can be seen among the hematopoietic cells.
    Bone marrow in a female F344/N rat from a 2-year study. Increased numbers of pale-staining vacuolated histiocytes (arrows) can be seen among the hematopoietic cells.
    Bone marrow in a female F344/N rat from a 2-year study. Increased numbers of pale-staining vacuolated histiocytes can be seen among the hematopoietic cells.
    Bone marrow in a female F344/N rat from a 2-year study. Increased numbers of pale-staining vacuolated histiocytes can be seen among the hematopoietic cells.
    Bone marrow in a female F344/N rat from a 2-year study. Increased numbers of pale-staining vacuolated histiocytes containing cholesterol crystals can be seen among the hematopoietic cells.
    Bone marrow in a female F344/N rat from a 2-year study. Increased numbers of pale-staining vacuolated histiocytes containing cholesterol crystals can be seen among the hematopoietic cells.
    Bone marrow in a female F344/N rat from a 2-year study. Increased numbers of pale-staining vacuolated histiocytes can be seen among the hematopoietic cells.
    Bone marrow in a female F344/N rat from a 2-year study. Increased numbers of pale-staining vacuolated histiocytes can be seen among the hematopoietic cells.

    Authors

    Michelle C. Cora, DVM, DACVP
    Veterinary Medical Officer
    NTP Clinical Pathologist
    NTP Clinical Pathology Group
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Gregory Travlos, DVM, DACVP
    Group Leader, Clinical Pathology Group
    Cellular and Molecular Pathology Branch
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Reviewers

    Armando R. Irizarry, DVM, PHD, DACVP
    Adjunct Associate Professor of Veterinary Anatomic and Clinical Pathology
    Department of Comparative Pathobiology
    Purdue University College of Veterinary Medicine
    West Lafayette, IN

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC