Reproductive System, Male

Prostate, Epithelium - Hyperplasia

    Narrative
    Prostate, Epithelium - Hyperplasia. Epithelial hyperplasia of the prostate in a male F344/N rat from a chronic study.
    Prostate, Epithelium - Hyperplasia. Epithelial hyperplasia of the prostate in a male F344/N rat from a chronic study.
    Prostate, Epithelium - Hyperplasia. Higher magnification of Figure 1. Proliferative epithelial cells have formed a thickened lining of the affected acini, and there is evidence of associated apoptosis (arrows) in a male F344/N rat from a chronic study.
    Prostate, Epithelium - Hyperplasia. Higher magnification of Figure 1. Proliferative epithelial cells have formed a thickened lining of the affected acini, and there is evidence of associated apoptosis (arrows) in a male F344/N rat from a chronic study.
    Prostate, Epithelium - Hyperplasia. Proliferative epithelial cells fill an acinus with multilocular areas of secretion in a male F344/N rat from a chronic study.
    Prostate, Epithelium - Hyperplasia. Proliferative epithelial cells fill an acinus with multilocular areas of secretion in a male F344/N rat from a chronic study.
    Prostate, Epithelium - Hyperplasia. Higher magnification of Figure 3. Epithelial hyperplasia of the prostate in a male F344/N rat from a chronic study.
    Prostate, Epithelium - Hyperplasia. Higher magnification of Figure 3. Epithelial hyperplasia of the prostate in a male F344/N rat from a chronic study.
    Prostate, Epithelium - Hyperplasia. Arrows indicate multiple areas of hyperplasia from a male TRAMP mouse in a 1-month study.
    Prostate, Epithelium - Hyperplasia. Arrows indicate multiple areas of hyperplasia from a male TRAMP mouse in a 1-month study.

    Authors:

    Dianne M. Creasy, PhD, Dip RCPath, FRCPath
    Dianne Creasy Consulting LLC
    Pipersville, PA

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Dipak K. Giri, DVM, PHD, DACVP
    Toxicologic Pathologist
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC
     

    Reviewers:

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC
     

    David E. Malarkey DVM, PhD, DACVP, FIATP
    Head, National Toxicology Program Pathology Group
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC