Nervous System
Brain - Axonopathy
Narrative
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Baker HJ, Lindsey JR, Weisbroth SH, eds. 1979. The Laboratory Rat, Vol 1: Biology and Diseases. Academic Press, New York.
Beirowski B, Adalbert R, Wagner D, Grumme DS, Addicks K, Ribchester RR, Coleman MP. 2006. The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves. BMC Neurosci 6:6.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/15686598Lubinska L. 1977. Early course of Wallerian degeneration in myelinated fibres of the rat phrenic nerve. Brain Res 130:47-63.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/884520Stoll G, Griffin JW, Li CY, Trapp BD. 1989. Wallerian degeneration in the peripheral nervous system: Participation of both Schwann cells and macrophages in myelin degradation. J Neurocytol 18:671-683.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/2614485Tabas I. 1997. Free cholesterol-induced cytotoxicity. A possible contributing factor to macrophage foam cell necrosis in advanced atherosclerotic lesions. Trends Cardiovasc Med 7:256-263.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/21235894Tenkova TI, Goldberg MP. 2007. A modified silver technique (de Olmos stain) for assessment of neuronal and axonal degeneration. Methods Mol Biol 399:31-39.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/18309923Waller A. 1850. Experiments on the section of glossopharyngeal and hypoglossal nerves of the frog and observations of the alternatives produced thereby in the structure of their primitive fibers. Philos Trans R Soc Lond Biol 140:423-429.
Spinal cord axonopathy in a male F344/N rat from a subchronic study. The arrow in this toluidine blue-stained section indicates the subtle pallor of the dorsal funiculus in which axonopathy is present.