Reproductive System, Male

Testis - Amyloid

    Narrative
    Testis - Amyloid in a male B6C3F1 mouse from a chronic study. There are perivascular accumulations of hemogenous, eosinophilic material in the interstitium (arrows).
    Testis - Amyloid in a male B6C3F1 mouse from a chronic study. Higher magnification of Figure 1 with perivascular accumulation of amyloid (arrow).
    Testis - Amyloid in a male Swiss CD-1 mouse from a chronic study. Widespread accumulation of amyloid with secondary tubular degeneration and necrosis.
    Testis - Amyloid in a male Swiss CD-1 mouse from a chronic study. Higher magnification of Figure 3 showing extensive amyloid deposition.

    Authors

    Dianne M. Creasy, PhD, Dip RCPath, FRCPath
    Dianne Creasy Consulting LLC
    Pipersville, PA

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Dipak K. Giri, DVM, PHD, DACVP
    Toxicologic Pathologist
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC

    Reviewers

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    David E. Malarkey DVM, PhD, DACVP, FIATP
    Head, National Toxicology Program Pathology Group
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC