Endocrine System

Pituitary Gland, Rathke's Cleft - Dilation

    Narrative
    Pituitary, Rathke's cleft - Dilation in a female F344/N rat from a chronic study. The dilated Rathke's cleft is filled with intensely eosinophilic proteinaceous material with cholesterol clefts (arrow) present at the edge of the dilated cleft., basic_html
    Pituitary, Rathke's cleft - Dilation in a female F344/N rat from a chronic study. Higher magnification of Figure 1 shows the dilated Rathke's cleft filled with intensely eosinophilic proteinaceous material and the cholesterol clefts (arrow) at the edge of the dilated cleft in greater detail., basic_html
    Pituitary, Rathke�s cleft - Dilation in a female F344/N rat from a chronic study. The dilated Rathke�s cleft contains pale eosinophilic proteinaceous material and erythrocytes (hemorrhage).

    Authors

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Thomas J. Rosol, DVM, PhD, DACVP
    Professor of Veterinary Biosciences
    Senior Advisor, Life Sciences, Technology Commercialization and Knowledge Transfer
    The Ohio State University
    Columbus, OH

    Deepa B. Rao, BVSc, MS, PhD, DABT, DACVP
    NTP Pathologist (Contractor)
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC