Esophagus - Edema

Esophagus - Edema in a male B6C3F1 mouse from a chronic study. Separation of tissues by clear space is visible (arrow).
Figure 1 of 2
comment:
Edema fluid, particularly fluid with a high protein content, appears as homogeneous eosinophilic material in extracellular spaces. It is often lost at processing and may appear as clear spaces in tissues ( Figure 1

recommendation:
Edema is diagnosed and graded. Edema as part of an inflammatory process, such as acute inflammation, is ordinarily not recorded separately unless it is a significant component of the lesion.references:
Mosier DA. 2007. Vascular disorders and thrombosis. In: Pathologic Basis of Veterinary Disease, 4th ed (McGavin MD, Zachary JF, eds). Mosby, St Louis, MO, 63-99.
Web page last updated on: November 17, 2014