Alimentary System

Stomach, Forestomach, Epithelium - Hyperplasia, [Focal, Diffuse]

    Narrative
    Stomach, Forestomach, Epithelium - Hyperplasia in a male F344/N rat from a subchronic study. The epithelial hyperplasia is diffuse.
    Stomach, Forestomach, Epithelium - Hyperplasia in a female F344/N rat from a chronic study. The epithelial hyperplasia is focal and papillary.
    Stomach, Forestomach, Epithelium - Hyperplasia in a male B6C3F1 mouse from a chronic study. Two exophytic, papillary foci of hyperplasia are present.
    Stomach, Forestomach, Epithelium - Hyperplasia in a male B6C3F1 mouse from a chronic study (higher magnification of Figure 3). A papillary focus of hyperplasia is present.
    Stomach, Forestomach - Normal limiting ridge in a male F344/N rat from a subchronic study.
    Stomach, Forestomach, Epithelium - Hyperplasia in a male B6C3F1 mouse from a subchronic study. Epithelial hyperplasia of the limiting ridge is present.
    Stomach, Forestomach, Epithelium - Hyperplasia in a male F344/N rat from a chronic study. Hyperplasia of the basal cells is present in the forestomach.
    Stomach, Forestomach, Epithelium - Hyperplasia in a male F344/N rat from a chronic study (higher magnification of Figure 7). Hyperplasia of the basal cells is present in the forestomach.

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC