Alimentary System

Stomach, Glandular Stomach, Epithelium - Hyperplasia, Atypical

    Narrative
    Stomach, Glandular stomach, Epithelium - Hyperplasia, Atypical in a female B6C3F1 mouse from a chronic study. There is an expansile focus of hyperplasia within the mucosa (arrow).
    Stomach, Glandular stomach, Epithelium - Hyperplasia, Atypical in a female B6C3F1 mouse from a chronic study (higher magnification of Figure 1). The epithelial cells within this hyperplastic focus are pleomorphic.

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC