Oral Mucosa, Gingiva - Ectopic Tissue

Oral mucosa, Gingiva - Ectopic tissue, Sebaceous gland in male F344/N rat from a chronic study. There are clusters of sebaceous glands in the gingiva.
Figure 1 of 4

Oral mucosa, Gingiva - Ectopic tissue, Sebaceous gland in male F344/N rat from a chronic study (higher magnification of Figure 1). The clusters of sebaceous glands in the gingiva are adjacent to a dilated duct.
Figure 2 of 4

Oral mucosa, Gingiva - Ectopic tissue, Sebaceous gland in male F344/N rat from a chronic study. There are clusters of sebaceous glands in the gingiva.
Figure 3 of 4
comment:
Ectopic sebaceous glands in the oral cavity are also known as Fordyce’s granules. Histologically, these are a collection of sebaceous glands unassociated with hair follicles ( Figure 1



recommendation:
This finding should be diagnosed as "Oral mucosa, gingiva - ectopic tissue, sebaceous gland." No grade is necessary.references:
Imaoka M, Satoh H, Kai K, Kajimura T, Furuhama K. 2003. Spontaneous ectopic sebaceous glands (Fordyce’s granules) in the oral mucosa of Sprague-Dawley rats. J Toxicol Pathol 16:253-257. Abstract: http://ci.nii.ac.jp/naid/10025851222
Yoshitomi K, Brown HR, Eustis S. 1990. Fordyce's granules of the incisor and molar gingival in F344 rats. Vet Pathol 27:432-438. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/2278131
Web page last updated on: November 17, 2014