Alimentary System

Oral Mucosa - Hyperplasia, Squamous

    Narrative
    Oral mucosa - Hyperplasia, Squamous in a female F344/N rat from chronic study. There is hyperplasia of the squamous epithelium of the hard palate.
    Oral mucosa - Hyperplasia, Squamous in a female F344/N rat from chronic study (higher magnification of Figure 1). There is hyperplasia of the squamous epithelium of the hard palate.
    Oral mucosa - Hyperplasia, Squamous in a male B6C3F1 mouse from a chronic study. The epithelium of the hard palate forms papillary folds.
    Oral mucosa - Hyperplasia, Squamous in a male F344/N rat from a chronic study. The gingival epithelium is hyperplastic, with thickening of the epithelial layer and numerous folds.

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC