Oral Mucosa - Hyperplasia, Squamous



comment:
Squamous hyperplasia of the oral mucosa is usually seen on the palate ( Figure 1



recommendation:
Squamous hyperplasia should be diagnosed and graded based on the size, thickness, and number of hyperplastic areas. The location of the lesion (e.g., gingival, palatal) should be noted in the pathology narrative. Associated lesions, such as inflammation, should not be diagnosed separately unless warranted by severity. Hyperkeratosis or ulceration associated with hyperplasia should not be diagnosed separately but should be a part of the lesion description in the pathology narrative.references:
Brown HR, Hardisty JF. 1990. Oral cavity, esophagus and stomach. In: Pathology of the Fischer Rat (Boorman GA, Montgomery CA, MacKenzie WF, eds). Academic Press, San Diego, CA, 9-30. Abstract: https://www.ncbi.nlm.nih.gov/nlmcatalog/9002563
Leininger JR, Jokinen MP, Dangler CA, Whiteley LO. 1999. Oral cavity, esophagus, and stomach. In: Pathology of the Mouse (Maronpot RR, ed). Cache River Press, St Louis, MO, 29-48. Abstract: http://www.cacheriverpress.com/books/pathmouse.htm
Yoshizawa K, Walker NJ, Jokinen MP, Brix AE, Sells DM, March T, Wyde ME, Orzech D, Haseman JK, Nyska A. 2004. Gingival carcinogenicity in female Harlan Sprague-Dawley rats following two-year oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds. Toxicol Sci 83:64-77. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/15509667
Web page last updated on: November 17, 2014