Salivary Gland - Fibrosis

comment:
Fibrosis can be found in and around the salivary glands ( Figure 1

recommendation:
Whenever present as the sole lesion, fibrosis should be diagnosed and graded. However, unless it is the end stage of a lesion, fibrosis is rarely seen without concurrent tissue damage or inflammation. Whenever it is a significant component of a degenerative, necrotic, or inflammatory lesion, fibrosis should be diagnosed and graded. Atrophy of glandular tissue that is considered secondary to fibrosis should not be diagnosed separately unless it is a prominent component of the lesion. Secondary lesions should be described in the pathology narrative.references:
Ackermann MR. 2007. Chronic inflammation and wound healing. In: Pathologic Basis of Veterinary Disease, 4th ed (McGavin MD, Zachary JF, eds). Mosby, St Louis, MO, 153-191.
Brown HR, Hardisty JF. 1990. Oral cavity, esophagus and stomach. In: Pathology of the Fischer Rat (Boorman GA, Montgomery CA, MacKenzie WF, eds). Academic Press, San Diego, CA, 9-30. Abstract: https://www.ncbi.nlm.nih.gov/nlmcatalog/9002563
Elmore S, Lanning L, Allison N, Vallant M, Nyska A. 2006. The transduction of rat submandibular glands by an adenoviral vector carrying the human growth hormone gene is associated with limited and reversible changes at the infusion site. Toxicol Pathol 34:385-392. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/16844666
Web page last updated on: November 17, 2014