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Salivary Gland - Necrosis

Image of necrosis in the salivary gland from a male F344/N rat in a subchronic study
Salivary gland - Necrosis in a male F344/N rat from a subchronic study. There is necrosis of the acinar cells (arrow) with inflammation.
Image of necrosis in the salivary gland from a male F344/N rat in a subchronic study
Salivary gland - Necrosis in a male F344/N rat from a subchronic study. There is necrosis of the acinar cells (arrow) with chronic active inflammation.
Image of necrosis in the salivary gland from a female F344/N rat in a subchronic study
Salivary gland - Necrosis in a female F344/N rat from a subchronic study. There is necrosis of an entire lobe of the salivary gland (arrow), consistent with an infarct.
Image of necrosis in the salivary gland from a female F344/N rat in a subchronic study
Salivary gland - Necrosis in a female F344/N rat from a subchronic study. There is necrosis of all the components of the salivary gland (consistent with an infarct), with inflammatory cells, mostly neutrophils.