Salivary Gland, Submandibular, Duct - Cytoplasmic Alteration

Normal submandibular salivary gland in a female B6C3F1 mouse from a chronic study. The arrow indicates a convoluted salivary gland duct.
Figure 1 of 3

Normal submandibular salivary gland in a male B6C3F1 mouse from a chronic study. The convoluted salivary gland ducts (arrow) contain more eosinophilic, cytoplasmic granules in males than in females (see Figure 1).
Figure 2 of 3
comment:
For a discussion on the sexual dimorphism of the salivary gland in rodents, please see the Introduction for this chapter. Examples of the normal female ( Figure 1



recommendation:
Cytoplasmic alteration should be diagnosed and graded based on the degree of increase in eosinophilic intracytoplasmic granules and number of convoluted (granular) ducts affected.references:
Botts S, Jokinen M, Gaillard ET, Elwell MR, Mann PC. 1999. Salivary, Harderian, and lacrimal glands. In: Pathology of the Mouse (Maronpot RR, ed). Cache River Press, St Louis, MO, 49-80. Abstract: http://www.cacheriverpress.com/books/pathmouse.htm
Seely JC. 1999. Kidney. In: Pathology of the Mouse (Maronpot RR, ed). Cache River Press, St Louis, MO, 207-234. Abstract: http://www.cacheriverpress.com/books/pathmouse.htm
Web page last updated on: November 17, 2014