Alimentary System

Tongue - Fibrosis

    Narrative
    Tongue - Fibrosis in a male F344/N rat from a subchronic study. There is an area of fibrosis with associated inflammation in the tongue (arrow).
    Tongue - Fibrosis in a male F344/N rat from a subchronic study (higher magnification of Figure 1). There is chronic inflammation and neovascularization within the area of fibrosis.

    Authors:

    Linda H. Kooistra, DVM, PhD, DACVP
    Pathologist
    Charles River Laboratories, Inc.
    Research Triangle Park, NC

    Abraham Nyska, DVM, Diplomate ECVP, Fellow IATP
    Expert in Toxicologic Pathology
    Visiting Full Professor of Pathology
    Sackler School of Medicine, Tel Aviv University Timrat Israel

    Reviewers:

    Joel R. Leininger, DVM, PhD
    Senior Pathologist
    MedImmune
    Washington, DC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC