Tongue - Inflammation









comment:
In NTP studies, there are five standard categories of inflammation: acute, suppurative ( Figure 3









Inflammation can be a treatment-related lesion but can also occur as a spontaneous background lesion. Suppurative inflammation is often due to foreign bodies ( Figure 6



recommendation:
Whenever present, inflammation should be diagnosed and given a severity grade. The appropriate modifier indicating the duration or type of inflammation (i.e., acute, suppurative, chronic, chronic active, or granulomatous) should be included in the diagnosis. Lesions consistent with an abscess are diagnosed as suppurative inflammation. If a foreign body is the cause of the inflammation, it should be diagnosed separately (foreign bodies are not graded). If bacteria or fungi are present, they should not be diagnosed separately but should be described in the narrative. Other associated lesions, such as hemorrhage, edema, or necrosis, should not be diagnosed separately unless warranted by severity but should be described in the pathology narrative.references:
Ackermann MR. 2007. Chronic inflammation and wound healing. In: Pathologic Basis of Veterinary Disease, 4th ed (McGavin MD, Zachary JF, eds). Mosby, St Louis, MO, 101-152.
Bertram TA, Markovits JE, Juliana MM. 1996. Non-proliferative lesions of the alimentary canal in rats GI-1. In: Guides for Toxicologic Pathology. STP/ARP/AFIP, Washington, DC, 1-16. Full Text: https://www.toxpath.org/docs/SSNDC/GINonproliferativeRat.pdf
Brown HR, Hardisty JF. 1990. Oral cavity, esophagus and stomach. In: Pathology of the Fischer Rat (Boorman GA, Montgomery CA, MacKenzie WF, eds). Academic Press, San Diego, CA, 9-30. Abstract: https://www.ncbi.nlm.nih.gov/nlmcatalog/9002563
Greaves P. 2007. Digestive system. In: Histopathology of Preclinical Toxicity Studies, 3rd ed. Academic Press, London, 334-456. Abstract: http://www.sciencedirect.com/science/book/9780444527714
Web page last updated on: November 24, 2014