Tooth - Fibrosis

Tooth - Fibrosis in a female Harlan Sprague-Dawley rat from a chronic study. There is fibrosis within the alveolar bone and a possible sequestrum of bone or osteodentin (arrow).
Figure 1 of 4

Tooth - Fibrosis in a female Harlan Sprague-Dawley rat from a chronic study (higher magnification of Figure 1). There is fibrosis within the alveolar bone and a possible sequestrum of bone or osteodentin (arrow).
Figure 2 of 4

Tooth - Fibrosis in a female B6C3F1 mouse from a chronic study. Fibrosis has replaced much of the alveolar bone.
Figure 3 of 4
comment:
Fibrosis within the alveolus ( Figure 1





recommendation:
Fibrosis should be diagnosed and graded when it is prominent in a lesion or if it has progressed to the point that fibrosis is the only lesion present. If fibrosis is a minor component of inflammation, it is not necessary to diagnose it separately, though it should be described in the pathology narrative.references:
Long PH, Leininger JR. 1999. Teeth. In: Pathology of the Mouse (Maronpot RR, ed). Cache River Press, St Louis, MO, 13-28. Abstract: http://www.cacheriverpress.com/books/pathmouse.htm
Web page last updated on: November 17, 2014