Adrenal Gland, Cortex - Hyperplasia, Subcapsular - Gallery

Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female Tg.AC (FVB/N) hemizygous mouse from a subchronic study. Early-stage subcapsular cell hyperplasia (SCH) is characterized by subcapsular foci of small, basophilic cells that extend into the zona fasciculata (arrow).

Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female Tg.AC (FVB/N) hemizygous mouse from a subchronic study (higher magnification of Figure 1). Early-stage subcapsular hyperplasia is composed primarily of smaller, more basophilic, fusiform, type A cells that extend into the zona fasciculate.

Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female B6C3F1/N mouse from a chronic study. Multiple foci of basophilic hyperplastic cells (arrows) are present in the subcapsular region.

Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 3). The subcapsular hyperplasia is characterized by proliferation of smaller, fusiform, basophilic type A (A) cells with nests of larger, paler, polygonal type B cells (B).

Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 3). Smaller, fusiform, basophilic type A cells are crowded together in a focus of subcapsular hyperplasia.

Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 3). Nests of larger, paler, polygonal type B cells are present in a focus of subcapsular hyperplasia.