Adrenal Gland, Cortex - Hyperplasia, Subcapsular - Gallery

Image of hyperplasia, subcapsular in the adrenal gland cortex from a female B6C3F1/N mouse in a subchronic study
Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female Tg.AC (FVB/N) hemizygous mouse from a subchronic study. Early-stage subcapsular cell hyperplasia (SCH) is characterized by subcapsular foci of small, basophilic cells that extend into the zona fasciculata (arrow).
Image of hyperplasia, subcapsular in the adrenal gland cortex from a female B6C3F1/N mouse in a subchronic study
Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female Tg.AC (FVB/N) hemizygous mouse from a subchronic study (higher magnification of Figure 1). Early-stage subcapsular hyperplasia is composed primarily of smaller, more basophilic, fusiform, type A cells that extend into the zona fasciculate.
Image of hyperplasia, subcapsular in the adrenal gland cortex from a female B6C3F1/N mouse in a chronic study
Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female B6C3F1/N mouse from a chronic study. Multiple foci of basophilic hyperplastic cells (arrows) are present in the subcapsular region.
Image of hyperplasia, subcapsular in the adrenal gland cortex from a female B6C3F1/N mouse in a chronic study
Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 3). The subcapsular hyperplasia is characterized by proliferation of smaller, fusiform, basophilic type A (A) cells with nests of larger, paler, polygonal type B cells (B).
Image of hyperplasia, subcapsular in the adrenal gland cortex from a female B6C3F1/N mouse in a chronic study
Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 3). Smaller, fusiform, basophilic type A cells are crowded together in a focus of subcapsular hyperplasia.
Image of hyperplasia, subcapsular in the adrenal gland cortex from a female B6C3F1/N mouse in a chronic study
Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 3). Nests of larger, paler, polygonal type B cells are present in a focus of subcapsular hyperplasia.
Image of hyperplasia, subcapsular in the adrenal gland cortex from a female B6C3F1/N mouse in a chronic study
Adrenal gland, Cortex - Hyperplasia, Subcapsular in a female B6C3F1/N mouse from a chronic study. Extensive subcapsular hyperplasia (arrows) forms a thick, almost circumferential band around the adrenal gland.
Image of hyperplasia, subcapsular in the adrenal gland cortex from a male B6C3F1/N mouse in a chronic study
Adrenal gland, Cortex - Hyperplasia, Subcapsular in a male B6C3F1/N mouse from a chronic study. A large subcapsular hyperplastic lesion is composed predominantly of polygonal type B cells (B) with fewer fusiform type A cells (A). M = medulla.