Endocrine System

Adrenal Gland - Cyst

    Narrative
    Adrenal gland, Cortex - Cyst in a female B6C3F1/N mouse from a chronic study. An adrenal cortical cyst (C), filled with amorphous pale eosinophilic material, compresses adjacent cortex and medulla.
    Adrenal gland, Cortex - Cyst in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). A single layer of well-differentiated, low columnar epithelial cells (arrow) lines an adrenocortical cyst.
    Adrenal gland, Cortex - Cyst in a female B6C3F1/N mouse from a chronic study. Cortical cyst (C) lined by cuboidal to columnar epithelial cells (arrows) contains flocculent, pale eosinophilic material.

    Authors

    Mark J. Hoenerhoff, DVM, PhD, DACVP
    Associate Professor
    Veterinary Pathologist, In Vivo Animal Core
    Unit for Laboratory Animal Medicine
    University of Michigan
    Ann Arbor, MI

    Georgette D. Hill, D.V.M., Ph.D.
    Toxicologic Pathologist/Assistant Pathology Program Manager
    Comparative Molecular Pathology Division
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC

    Margarita M. Gruebbel, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Thomas J. Rosol, DVM, PhD, DACVP
    Professor of Veterinary Biosciences
    Senior Advisor, Life Sciences, Technology Commercialization and Knowledge Transfer
    The Ohio State University
    Columbus, OH

    Gordon Flake, MD
    Staff Scientist
    NTP Pathologist
    Cellular and Molecular Pathology Branch
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC