Adrenal Gland - Fibrosis







comment:
Adrenal gland fibrosis ( Figure 1


















recommendation:
Adrenal gland fibrosis should be diagnosed and assigned a severity grade. A site modifier (i.e., cortex, medulla, or capsule) should be included in the diagnosis. If it is present in both the cortex and medulla, the site modifier may be omitted and the location described in the pathology narrative. A distribution modifier (e.g., focal) may be included in the diagnosis if necessary. Fibrosis secondary to other lesions (e.g., inflammation or necrosis) should not be diagnosed separately unless warranted by severity. Features of fibrosis (e.g., mineralization or pigment) should not be diagnosed separately, though they should be described in the pathology narrative.references:
National Toxicology Program. 1997. NTP TR-459. Toxicology and Carcinogenesis Studies of t-Butylhydroquinone (CAS No. 1948-33-0) in F344/N Rats and B6C3F1 Mice (Feed Studies). NTP, Research Triangle Park, NC. Abstract: https://ntp.niehs.nih.gov/go/6062
National Toxicology Program. 1999. NTP TR-481. Toxicology and Carcinogenesis Studies of Oleic Acid Diethanolamine Condensate (CAS No. 93-83-4) in F344/N Rats and B6C3F1 Mice (Dermal Studies). NTP, Research Triangle Park, NC. Abstract: https://ntp.niehs.nih.gov/go/9764
National Toxicology Program. 2010. NTP TR-557. Toxicology and Carcinogenesis Studies of β-Myrcene (CAS No. 123-35-3) in F344/N Rats and B6C3F1 Mice (Gavage Studies). NTP, Research Triangle Park, NC. Abstract: https://ntp.niehs.nih.gov/go/33584
National Toxicology Program. 2010. NTP TR-559. Toxicology and Carcinogenesis Studies of 2,3',4,4',5-Pentachlorobiphenyl (PCB 118) (CAS No. 31508-00-6) in Female Harlan Sprague-Dawley Rats (Gavage Studies). NTP, Research Triangle Park, NC. Abstract: https://ntp.niehs.nih.gov/go/33539
National Toxicology Program. 2011. NTP TR-563. Toxicology and Carcinogenesis Studies of Pulegone (CAS No. 89-82-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies). NTP, Research Triangle Park, NC. Abstract: https://ntp.niehs.nih.gov/go/34851
Web page last updated on: January 02, 2015