Pancreatic Islets - Angiectasis
comment:Angiectasis typically involves irregular dilated spaces that contain erythrocytes and/or plasma with a negligible endothelial cell lining. This is a spontaneous change with no known association with, or exacerbation by, treatment. Typically only one affected islet is seen in a section. There may also be hemosiderin pigment along with erythrocytes ( Figure 4 ).
recommendation:When present, this change should be diagnosed and graded. A severity grade will most often be minimal if the angiectasis is not widespread. If angiectasis or related changes are observed in other tissues, a comment to this effect should be added to the pathology narrative. If hemosiderin is present, a concurrent diagnosis of pigment is not necessary.
Boorman GA, Sills RC. 1999. Exocrine and endocrine pancreas. In: Pathology of the Mouse: Reference and Atlas (Maronpot RR, Boorman GA, Gaul BW, eds). Cache River Press, Vienna, IL, 185-206. Abstract: http://www.cacheriverpress.com/books/pathmouse.htm
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