Endocrine System

Parathyroid Gland - Hyperplasia, Diffuse

    Narrative
    Parathyroid gland - Hyperplasia, Diffuse in a male F344/N rat from a chronic study. The parathyroid gland is increased in volume.
    Parathyroid gland - Hyperplasia, Diffuse in a male F344/N rat from a chronic study. Enlarged nests of mildly hypertrophic parathyroid chief cells (arrows) have an increased cytoplasmic-to-nuclear ratio, and the intervening fibroreticular stroma is less apparent than normal.

    Authors

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Georgette D. Hill, D.V.M., Ph.D.
    Toxicologic Pathologist/Assistant Pathology Program Manager
    Comparative Molecular Pathology Division
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC

    Reviewers

    Thomas J. Rosol, DVM, PhD, DACVP
    Professor of Veterinary Biosciences
    Senior Advisor, Life Sciences, Technology Commercialization and Knowledge Transfer
    The Ohio State University
    Columbus, OH

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC