Endocrine System

Pituitary Gland - Cyst

    Narrative
    Pituitary Gland - Cyst in a female Harlan Sprague-Dawley rat from a chronic study. A cyst filled with pale eosinophilic proteinaceous fluid is present in the pars distalis.
    Pituitary Gland - Cyst in a female Harlan Sprague-Dawley rat from a chronic study. Higher magnification of Figure 1 shows that the cyst is partially lined by tall cuboidal ciliated epithelium.
    Pituitary Gland - Cyst in a male F344/n rat from a chronic study. The cysts in the pars distalis are lined by ciliated cuboidal cells and contain flocculant eosinophilic proteinaceous material.
    Pituitary Gland - Cyst, multiple in a female F344/N rat from a chronic study. Multiple cysts are present in the pars nervosa (arrows), as well as a dilated persistent Rathke's cleft (asterisks), are filled with eosinophilic proteinaceous material., basic_html
    Pituitary Gland - Cyst, multiple in a female F344/N rat from a chronic study. Higher magnification of Figure 4 shows the cysts in the pars nervosa (arrows) and the dilated persistent Rathke's cleft (asterisks) in greater detail., basic_html
    Pituitary Gland - Cysts, multiple in a female F344/N rat from a chronic study. Higher magnification of Figure 5 shows the epithelium-lined cysts are present in the pars nervosa.

    Authors

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Thomas J. Rosol, DVM, PhD, DACVP
    Professor of Veterinary Biosciences
    Senior Advisor, Life Sciences, Technology Commercialization and Knowledge Transfer
    The Ohio State University
    Columbus, OH

    Deepa B. Rao, BVSc, MS, PhD, DABT, DACVP
    NTP Pathologist (Contractor)
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC