Reproductive System, Female

Clitoral Gland - Atrophy

    Narrative
    Clitoral gland - Atrophy, Unilateral in a female B6C3F1/N mouse from a chronic study. The gland on the left is atrophied, while the gland on the right is within normal limits.
    Clitoral gland - Atrophy in a female F344/N rat from a chronic study. There is a reduced amount of glandular tissue and more numerous ducts.
    Clitoral gland - Atrophy in a female F344/N rat from a chronic study (higher magnification of Figure 2). The amount of glandular tissue is decreased, and the ducts are prominent.
    Clitoral gland - Atrophy in a female F344/N rat from a chronic study. Some of the glandular tissue has been replaced by fibrous connective tissue.
    Clitoral gland - Atrophy in a female F344/N rat from a chronic study (higher magnification of Figure 4). There is an increase in intervening fibrous connective tissue with a reduction in glandular tissue.

    Authors

    Gabrielle Willson, BVMS, Dip RC Path, FRC Path, MRCVS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Karen Y. Cimon, DVM, MS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Gordon Flake, MD
    Staff Scientist
    NTP Pathologist
    Cellular and Molecular Pathology Branch
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    Reviewers

    Karen S. Regan, DVM, DABT, DACVP
    Pathologist
    Regan Path/Tox Services, Inc.
    Ashland, OH  

    Darlene Dixon, DVM, PhD, DACVP, Fellow, IATP
    Group Leader, Molecular Pathogenesis Group
    National Toxicology Program Laboratory
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC