Reproductive System, Female

Ovary, Follicle - Cyst

    Narrative
    Ovary, Follicle - Cyst in a female B6C3F1/N mouse from a chronic study. A large ovarian follicular cyst appears as a distended fluid-filled space lacking an oocyte.
    Ovary, Follicle - Cyst in a female B6C3F1/N mouse from a chronic study (higher magnification of Figure 1). The cyst wall is lined by one to two layers of cuboidal or flattened granulosa cells.

    Authors

    Gabrielle Willson, BVMS, Dip RC Path, FRC Path, MRCVS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Karen Y. Cimon, DVM, MS
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Karen S. Regan, DVM, DABT, DACVP
    Pathologist
    Regan Path/Tox Services, Inc.
    Ashland, OH  

    Darlene Dixon, DVM, PhD, DACVP, Fellow, IATP
    Group Leader, Molecular Pathogenesis Group
    National Toxicology Program Laboratory
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC