Bone Marrow - Necrosis - Gallery
Bone marrow necrosis in a female B6C3F1 mouse from a chronic study (low magnification).
Bone marrow in a female B6C3F1 mouse from a chronic study (higher magnification of Figure 1) showing bone marrow necrosis characterized by remnants of hematopoietic cells with indistinct borders, nuclear pyknosis, karyolysis, and karyorrhexis.
Bone marrow in male B6C3F1 mouse from a chronic study (low magnification), showing a large well-demarcated eosinophilic area representing necrosis (asterisk). Arrows represent the line of demarcation between viable cells and the area of necrosis.
Bone marrow in a male B6C3F1 mouse from a chronic study (higher magnification of Figure 3), showing the area of necrosis (asterisk) and the line of demarcation (arrows) between the viable cells and the area of necrosis.
Bone marrow in a male B6C3F1 mouse from a chronic study (low magnification), showing normal hematopoietic cells (white asterisk) transitioning to a large area of necrosis characterized by loss of cellular detail and areas of amorphous eosinophilic debris (black asterisk).
