Bone Marrow - Necrosis - Gallery

Bone marrow in a female B6C3F1 mouse from a chronic study (higher magnification of Figure 1) showing bone marrow necrosis characterized by remnants of hematopoietic cells with indistinct borders, nuclear pyknosis, karyolysis, and karyorrhexis.

Bone marrow in male B6C3F1 mouse from a chronic study (low magnification), showing a large well-demarcated eosinophilic area representing necrosis (asterisk). Arrows represent the line of demarcation between viable cells and the area of necrosis.