Hepatobiliary System

Liver - Focus

    Narrative
    Basophilic focus (arrows) in a male F344/N rat from a subchronic study.
    Basophilic focus in a male F344/N rat from a subchronic study (higher magnification of Figure 1).
    Eosinophilic focus (arrows) in a male B6C3F1 mouse from a chronic study.
    Eosinophilic focus in a male B6C3F1 mouse from a chronic study (higher magnification of Figure 3).
    Clear cell focus in a female B6C3F1 mouse from a chronic study.
    Clear cell focus in a female B6C3F1 mouse from a chronic study (higher magnification of Figure 5).
    Mixed cell focus in a female Harlan Sprague-Dawley rat from a chronic study.
    Mixed cell focus in a female Harlan Sprague-Dawley rat from a chronic study (higher magnification of Figure 7).
    Mixed cell focus in a male B6C3F1 mouse from a chronic study.
    Mixed cell focus in a male B6C3F1 mouse from a chronic study (higher magnification of Figure 9).

    Author

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    John Cullen, VMD, PhD, DACVP, FIATP
    Anatomic Pathology, Professor
    North Carolina State University College of Veterinary Medicine
    Raleigh, NC

    David E. Malarkey DVM, PhD, DACVP, FIATP
    Head, National Toxicology Program Pathology Group
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC