Spleen - Atrophy - Gallery
Spleen, White pulp - Atrophy in a female F344/N rat from a subchronic study. Overall area and cellularity of the white pulp (periarteriolar lymphatic sheaths and follicles) are decreased (arrows), although the marginal zones appear to be within normal limits.
Spleen, White pulp - Atrophy in a female F344/N rat from a subchronic study (higher magnification of Figure 1). Decreased cellularity and area of the periarteriolar lymphatic sheath region (arrows) are evident.
Spleen - Atrophy in a female B6C3F1/N mouse from a subchronic study. Both red pulp (arrow) and white pulp (follicles, periarteriolar lymphatic sheaths, marginal zones) are atrophied.