Spleen - Necrosis - Gallery

Spleen - Necrosis in a male F344/N rat from a chronic study. A large necrotic focus (arrow) is present with the spleen.

Spleen - Necrosis in a male F344/N rat from a chronic study (higher magnification of Figure 1). Necrosis is bordered by foci of hemorrhage (arrowhead) and fibrous connective tissue (arrow).

Spleen - Necrosis in a male B6C3F1/N mouse from a chronic study. A large necrotic focus (arrow) is present with the spleen.

Spleen - Necrosis in a male B6C3F1/N mouse from a chronic study (higher magnification of Figure 3). The necrotic focus is bordered by a mixed inflammatory infiltrate (arrow), fibrosis (arrowhead), and dilated blood vessels.