Thymus - Mineralization
comment:Mineralization does not typically occur as a primary lesion in the thymus. However, it can occur secondary to renal and/or parathyroid disease (metastatic mineralization) or with thymic necrosis (dystrophic mineralization). This lesion is characterized by variable amounts of densely basophilic, amorphous, and/or granular material ( Figure 1 and Figure 2 , arrows). Mineral may occur as multifocal lesions within the thymus with renal or parathyroid disease or may occur within necrotic foci.
recommendation:Thymic mineralization should be diagnosed and graded if associated with renal and/or parathyroid disease. Mineralization associated with thymic necrosis should not be diagnosed separately unless warranted by severity, but should be described in the pathology narrative.
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Web page last updated on: February 03, 2015