Integumentary System

Skin, Hair Follicle - Dilatation and Cyst

    Narrative
    Hair follicle dilatation-ectatic hair follicles with intraluminal keratin (arrows) in a male B6C3F1 mouse from a chronic study.
    Hair follicle dilatation-ectatic hair follicles with intraluminal keratin (arrows) in a male B6C3F1 mouse from a chronic study.
    Epithelial cyst-flattened squamous epithelium surrounding a core of inspissated keratin in a male B6C3F1 mouse from a chronic study.
    Epithelial cyst-ruptured cyst lining and resulting granulomatous inflammation in a female B6C3F1 mouse from a chronic study.

    Authors

    Molly H. Boyle, DVM, MPH, DACVP
    Toxicologic Pathologist
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC

    Georgette D. Hill, D.V.M., Ph.D.
    Toxicologic Pathologist
    Assistant Pathology Program Manager
    Integrated Laboratory Systems, Inc. Research Triangle Park, NC

    Reviewers

    Michael R. Elwell, DVM, PhD, DACVP
    Anatomic Pathologist
    Covance Laboratories, Inc.
    Washington, D.C.

    David E. Malarkey DVM, PhD, DACVP, FIATP
    Head, National Toxicology Program Pathology Group
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC