Reproductive System, Male

Epididymis, Duct - Atrophy

    Narrative
    Epididymis, Duct - Atrophy. Decreased diameter of empty ducts in the body and tail of the epididymis in a male F344/N rat from a subchronic study.
    Epididymis, Duct - Atrophy. This higher magnification of Figure 1 shows the scalloped outline of reduced epididymal ducts in a male F344/N rat from a subchronic study.
    Epididymis, Duct - Atrophy. Empty, collapsed ducts surrounded by abundant mesenchymal tissue in a male F344/N rat from a chronic study.
    Epididymis, Duct - Atrophy. Higher magnification of Figure 3 showing collapsed ducts surrounded by myofibrotic mesenchymal tissue in a male F344/N rat from a chronic study.

    Authors:

    Dianne M. Creasy, PhD, Dip RCPath, FRCPath
    Dianne Creasy Consulting LLC
    Pipersville, PA

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Dipak K. Giri, DVM, PhD, DACVP
    Toxicologic Pathologist
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC

    Reviewers:

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist, NTP Pathologist
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC

    David E. Malarkey DVM, PhD, DACVP, FIATP
    Head, National Toxicology Program Pathology Group
    Cellular and Molecular Pathology Branch
    Division of the National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC