U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Skip to Main Navigation
Skip to Page Content
Skip to Atlas Navigation


Accessory sex organs in the male reproductive system, in addition to the prostate, include the seminal vesicles, preputial glands, ductus deferens, and penis. These tissues can exhibit direct and indirect (often hormonal) pleotrophic pathologic responses. A change in one reproductive tissue is often accompanied by changes in other reproductive tissues. The majority of the male reproductive tissues are paired, allowing identification of unilateral versus bilateral responses. Artifacts are rare.

Information on the following lesions is available in this section:

Epididymis - Amyloid
Epididymis, Duct - Atrophy
Epididymis, Duct - Dilation
Epididymis, Duct - Exfoliated Germ Cell
Epididymis, Epithelium - Apoptosis
Epididymis, Epithelium - Degeneration
Epididymis, Epithelium - Karyomegaly
Epididymis, Epithelium - Vacuolation
Epididymis - Hypospermia
Epididymis - Inflammation
Epididymis - Sperm Granuloma
Epididymis - Sperm Stasis
Epididymis - Spermatocele

Click the tabs in the left-hand column.


Creasy DM, Foster P. 1991. Male reproductive system. In: Handbook of Toxicologic Pathology (Haschek E, Rousseaux C, eds). Academic Press, New York, 829-889.
Abstract: http://www.sciencedirect.com/science/book/9780123302151

Creasy D, Bube A, de Rijk E, Kandori H, Kuwahara M, Masson R, Nolte T, Reams R, Regan K, Rehm S, Rogerson P, Whitney K. (2012). Proliferative and nonproliferative lesions of the rat and mouse male reproductive system. Toxicol Pathol 40:40S-121S.
Abstract: https://doi.org/10.1177/0192623312454337