Testis - Fibrosis

comment:
While modest amounts of fibrosis can be seen in chronic inflammation of the testis, the degree of fibrosis present in Figure 1

recommendation:
Fibrosis should be diagnosed and graded if it represents a primary lesion and when warranted by extent and severity and should be discussed in the pathology narrative if the incidence and/or severity appears to be related to chemical administration. If present in both testes, it should be diagnosed as bilateral.references:
Barroso-Moguel R, Méndez-Armenta M, Villeda-Hernàndez J. 1994. Testicular lesions by chronic administration of cocaine in rats. J Appl Toxicol 14:37-41. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/8157868
Bomhard E, Vogel O, Loser E. 1987. Chronic effects on single and multiple oral and subcutaneous cadmium administrations on the testes of Wistar rats. Cancer Lett 36:307-315. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/3652031
Creasy D, Bube A, de Rijk E, Kandori H, Kuwahara M, Masson R, Nolte T, Reams R, Regan K, Rehm S, Rogerson P, Whitney K. (2012). Proliferative and nonproliferative lesions of the rat and mouse male reproductive system. Toxicol Pathol 40:40S-121S. Abstract: https://doi.org/10.1177/0192623312454337
Gouveia MA. 1988. The testes in cadmium intoxication: Morphological and vascular aspects. Andrologia 20:225-231. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/3177901
Jana K, Samanta PK. 2006. Evaluation of single intratesticular injection of calcium chloride for nonsurgical sterilization in adult albino rats. Contraception 73:289-300. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/16472573
Web page last updated on: January 18, 2019