Testis, Rete Testis - Dilation
comment:
Dilation of the rete testis ( Figure 1
recommendation:
Rete testis dilation should be diagnosed and graded and should be discussed in the pathology narrative if the incidence and/or severity appears to be related to chemical administration. Bilateral involvement should be diagnosed when present. Attention should be paid to any evidence of gross or microscopic lesions within the initial segment of the epididymis or the epididymal fat pad (location of the efferent ducts) that may reflect sperm granulomas, sperm stasis, or dilated ducts. Rete testis dilation may be associated with seminiferous tubular dilation and/or germinal epithelial atrophy, since these may be a consequence of obstruction of fluid outflow.related links:
Testis, Seminiferous Tubule - DilationTestis - Sperm Stasis
Male Reproductive System - Introduction
references:
Creasy D, Bube A, de Rijk E, Kandori H, Kuwahara M, Masson R, Nolte T, Reams R, Regan K, Rehm S, Rogerson P, Whitney K. (2012). Proliferative and nonproliferative lesions of the rat and mouse male reproductive system. Toxicol Pathol 40:40S-121S. Abstract: https://doi.org/10.1177/0192623312454337
La DK, Johnson CA, Creasy DM, Hess RA, Baxter E, Pereira M, Snook SS. 2011. Efferent duct toxicity with secondary testicular changes in rats following administration of a novel leukotriene A4 hydrolase inhibitor. Toxicol Pathol 40:705-714. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/22552396
Piner J, Sutherland M, Millar M, Turner K, Newall D, Sharpe RM. 2002. Changes in vascular dynamics of the adult rat testis leading to transient accumulation of seminiferous tubule fluid after administration of a novel 5-hydroxytryptamine (5HT) agonist. Reprod Toxicol 16:141-150. Abstract: http://www.ncbi.nlm.nih.gov/pubmed/11955945
Web page last updated on: July 28, 2014