Musculoskeletal System

Bone - Increased Osteoid

    Narrative
    Bone - Increased osteoid in a male F344/N rat from a chronic study There is deposition of unmineralized osteoid along the existing trabeculae.
    Bone - Increased osteoid in a male F344/N rat from a chronic study (higher magnification of Figure 1). Increased numbers of osteoblasts are evident along the surface of new bone formation (arrows).

    Authors

    Mark J. Hoenerhoff, DVM, PhD, DACVP
    Associate Professor
    In Vivo Animal Core,Unit for Laboratory Animal Medicine
    University of Michigan
    Ann Arbor, MI

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Philip H. Long, DVM, PhD, DACVP
    Presiden and Senior Pathologist
    Vet Path Services, Inc.
    Mason, OH

    Joel R. Leininger, DVM, PhD, DACVP
    JRL Consulting, LLC
    Chapel Hill, NC