Musculoskeletal System

Bone - Inflammation

    Narrative
    Bone - Inflammation, Chronic in the bone of a male F344/N rat from a chronic study. Bone resorption is associated with inflammation.
    Bone - Inflammation, Chronic in a male B6C3F1/N mouse from a chronic study. Inflammatory cells surround a piece of bone that is undergoing resorption (sequestrum).
    Bone - Inflammation, Chronic in a male F344/N rat from a chronic study. Reactive bone is arranged in an orderly pattern, with bony trabeculae arranged perpendicular to the adjacent mature cortical bone (arrows).

    Authors

    Mark J. Hoenerhoff, DVM, PhD, DACVP
    Associate Professor
    In Vivo Animal Core,Unit for Laboratory Animal Medicine
    University of Michigan
    Ann Arbor, MI

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Reviewers

    Philip H. Long, DVM, PhD, DACVP
    Presiden and Senior Pathologist
    Vet Path Services, Inc.
    Mason, OH

    Joel R. Leininger, DVM, PhD, DACVP
    JRL Consulting, LLC
    Chapel Hill, NC