Musculoskeletal System

Skeletal Muscle - Atrophy

    Narrative
    muscle - Atrophy in a male F344/N rat from a chronic study. Individual hypereosinophilic muscle fibers of reduced diameter are sometimes surrounded by clear spaces.
    Skeletal muscle - Atrophy in a male B6C3F1/N mouse from a subchronic study. Note the reduction in myofiber diameter of the affected fibers (top) compared with the more normal myofibers along the bottom.

    Authors

    Torrie A. Crabbs, DVM, DACVP
    Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC  

    Reviewers

    Philip H. Long, DVM, PhD, DACVP
    Presiden and Senior Pathologist
    Vet Path Services, Inc.
    Mason, OH

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC