Musculoskeletal System

Skeletal Muscle - Edema

    Narrative
    Skeletal muscle - Edema in a male F344/N rat from a chronic study. Muscle fibers and muscle bundles are separated by expanded interstitial spaces filled with pale pink material.
    Skeletal muscle - Edema in a male F344/N rat from a chronic study (higher magnification of Figure 1). There are separated muscle fibers and muscle bundles due to an accumulation of pale pink interstitial material.
    Skeletal muscle - Edema in a male F344/N rat from a chronic study. A longitudinal section of skeletal muscle shows expansion of the interstitial spaces due to an accumulation of poorly stained edema fluid.
    Skeletal muscle - Edema in a male F344/N rat from a chronic study (higher magnification of Figure 3). Interstitial spaces are expanded by poorly stained edema fluid.
    Skeletal muscle - Normal in a male B6C3F1/N mouse from a subchronic study. Expanded interstitial space caused by fixation and/or sectioning artifact.

    Authors

    Torrie A. Crabbs, DVM, DACVP
    Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC  

    Reviewers

    Philip H. Long, DVM, PhD, DACVP
    Presiden and Senior Pathologist
    Vet Path Services, Inc.
    Mason, OH

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC