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Skeletal Muscle - Fibrosis - Gallery

Image of fibrosis in the skeletal muscle from a male Harlan Sprague-Dawley rat in a subchronic study
Skeletal muscle - Fibrosis in a male Harlan Sprague-Dawley rat from a subchronic study. Early change consists of increased perimysial deposits of pale eosinophilic material (immature collagen).
Image of fibrosis in the skeletal muscle from a male Harlan Sprague-Dawley rat in a subchronic study
Skeletal muscle - Fibrosis in a male Harlan Sprague-Dawley rat from a subchronic study. Note the perimysial proliferation of fibroblasts and early collagen deposition.
Image of fibrosis in the skeletal muscle from a male Harlan Sprague-Dawley rat in a subchronic study
Skeletal muscle - Fibrosis in a male Harlan Sprague-Dawley rat from a subchronic study (higher magnification of Figure 2). There is deposition of perimysial connective tissue and attenuation of several muscle fibers.
Image of fibrosis in the skeletal muscle from a male F344/N rat in a chronic study
Skeletal muscle - Fibrosis in a male F344/N rat from a chronic study. There is marked fibrosis with attenuation and loss of muscle bundles.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.