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Skeletal Muscle - Fibrosis - Gallery

Image of fibrosis in the skeletal muscle from a male Harlan Sprague-Dawley rat in a subchronic study
Skeletal muscle - Fibrosis in a male Harlan Sprague-Dawley rat from a subchronic study. Early change consists of increased perimysial deposits of pale eosinophilic material (immature collagen).
Image of fibrosis in the skeletal muscle from a male Harlan Sprague-Dawley rat in a subchronic study
Skeletal muscle - Fibrosis in a male Harlan Sprague-Dawley rat from a subchronic study. Note the perimysial proliferation of fibroblasts and early collagen deposition.
Image of fibrosis in the skeletal muscle from a male Harlan Sprague-Dawley rat in a subchronic study
Skeletal muscle - Fibrosis in a male Harlan Sprague-Dawley rat from a subchronic study (higher magnification of Figure 2). There is deposition of perimysial connective tissue and attenuation of several muscle fibers.
Image of fibrosis in the skeletal muscle from a male F344/N rat in a chronic study
Skeletal muscle - Fibrosis in a male F344/N rat from a chronic study. There is marked fibrosis with attenuation and loss of muscle bundles.