Musculoskeletal System

Skeletal Muscle - Regeneration

    Narrative
    Skeletal muscle - Regeneration in a male Harlan Sprague-Dawley rat from a subchronic study. Myoblasts and cytoplasmic basophilia (arrows) characterize regeneration of a previously damaged muscle fiber.
    Skeletal muscle - Regeneration in a male Harlan Sprague-Dawley rat from a subchronic study. Myoblasts with vesiculated nuclei and prominent nucleoli in a regenerating muscle fiber (arrows) are present.
    Skeletal muscle - Regeneration in a male Harlan Sprague-Dawley rat from a subchronic study. A row of internal nuclei (arrow) is present within a regenerating muscle fiber that has lost its basophilia.
    Skeletal muscle - Regeneration in a male Harlan Sprague-Dawley rat from a subchronic study. A row of internal vesiculated nuclei (arrow) is present in a regenerating muscle fiber; myofiber degeneration is present in a nearby muscle fiber (arrowhead).

    Authors

    Torrie A. Crabbs, DVM, DACVP
    Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC  

    Reviewers

    Philip H. Long, DVM, PhD, DACVP
    Presiden and Senior Pathologist
    Vet Path Services, Inc.
    Mason, OH

    Amy Brix, DVM, PhD, DACVP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC

    Robert R. Maronpot, DVM, MS, MPH, DACVP, DABT, FIATP
    Senior Pathologist
    Experimental Pathology Laboratories, Inc.
    Research Triangle Park, NC