U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Skip to Main Navigation
Skip to Page Content
Skip to Atlas Navigation

Brain, Leptomeninges - Hamartoma, Lipomatous

Image of Hamartoma, lipomatous in the Brain from a Male B6C3F1 Mouse in a 2 year Study
Leptomeningeal lipomatous hamartoma in an untreated male B6C3F1 mouse from a 2-year study. The arrow identifies the location of the lipomatous mass.
Figure 1 of 1
next arrow
View all images

comment:

Figure 1image opens in a pop-up window depicts a neurodevelopmental anomaly. This midline leptomeningeal lipomatous hamartoma is located at the base of the cingulate gyrus, immediately above the corpus callosum and septal nuclei. Consisting of normal white adipocytes, it is in the common location for a lipomatous hamartoma. The expansion of the hamartoma has had little compressive effect on adjacent structures and was not accompanied by noticeable clinical neurological signs. This type of hamartoma is uncommon in rodent studies. It is not to be confused with a lipoma or liposarcoma.

recommendation:

Lipomatous hamartomas should be diagnosed in NTP studies and the subsite specified.

references:

Krinke GJ, Kaufmann W, Mahrous AT, Schaetti P. 2000. Morphologic characterization of spontaneous nervous system tumors in mice and rats. Toxicol Pathol 28:178-192.
Abstract: http://www.ncbi.nlm.nih.gov/pubmed/10669006

Back to top

Web page last updated on: June 13, 2014