Nervous System

Spinal Cord - Demyelination

    Narrative
    Mouse spinal cord depicting bilateral demyelination of the lateral columns (arrows) in a mouse (age, strain, and gender unknown).
    Sciatic nerve myelin digestion chamber containing an intact axon between arrowheads in a rat (age, strain, and gender unknown).

    Authors

    Peter Little, DVM, MS, PhD, DACVP
    Neuropathology Consultant
    Experimental Pathology Laboratories, Inc.  
    Research Triangle Park, NC

    Deepa B. Rao, BVSc, MS, PhD, DABT, DACVP
    NTP Pathologist (Contractor)
    Integrated Laboratory Systems, Inc.
    Research Triangle Park, NC

    Reviewers

    James P. Morrison, DVM, DACVP
    Scientific Director
    Charles River Laboratories, Pathology Associates
    Research Triangle Park, NC

    Robert C. Sills, DVM, PhD, FIATP
    Chief, Cellular and Molecular Pathology Branch
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC