Lung - Amyloid



comment:
Amyloid ( Figure 1



recommendation:
Because this lesion is biologically important, Lung - Amyloid should be diagnosed and assigned a severity grade whenever present. The location of the amyloid deposits should be indicated in the diagnosis by using a site modifier. Any secondary lesions, such as necrosis or degeneration, should not be diagnosed separately unless warranted by severity but should be described in the pathology narrative.references:
Buxbaum JN. 2004. The systemic amyloidoses. Curr Opin Rheumatol 16:67-75. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/14673392
Frith CH, Manik C. 1991. Incidence, distribution, and morphology of amyloidosis in Charles Rivers CD-1 mice. Toxicol Pathol 19:123-127. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/1771365
Higuchi K, Matsumura A, Honma A, Takeshita S, Hashimoto K, Hosokawa M, Yasuhira K, Takeda T. 1983. Systemic senile amyloid in senescence-accelerated mice. A unique fibril protein demonstrated in tissues from various organs by the unlabeled immunoperoxidase method. Lab Invest 48:231-240. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/6337302
Homburger F, Russfield AB, Weisburger JH, Lim S, Chak SP, Weisburger EK. 1975. Aging changes in CD-1 HaM/ICR mice reared under standard laboratory conditions. J Natl Cancer Inst 55:37-45. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/169366
Takeshita S, Hosokawa M, Irino M, Higuchi K, Shimizu K, Yasuhira K, Takeda T. 1982. Spontaneous age-associated amyloidosis in senescence-accelerated mouse (SAM). Mech Ageing Dev 20:13-23. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/7176700
Westermark P, Benson MD, Buxbaum JN, Cohen AS, Frangione B, Ikeda S, Masters CL, Merlini G, Saraiva MJ, Sipe JD. 2007. A primer of amyloid nomenclature. Amyloid 14:179-183. Abstract: https://www.ncbi.nlm.nih.gov/pubmed/17701465
Web page last updated on: December 02, 2015