Respiratory System

Lung - Hemorrhage

    Narrative
    Lung - Hemorrhage in a male F344/N rat from a chronic study. There are small numbers of extravasated erythrocytes around pulmonary veins (arrows).
    Lung - Hemorrhage in a male F344/N rat from a chronic study (same animal as in Figure 1). Erythrocytes are present in the perivascular space around a pulmonary vein.
    Lung - Hemorrhage in a male F344/N rat from a chronic study. The hemorrhage is associated with chronic inflammation and fibrosis.
    Lung - Hemorrhage in a male F344/N rat from a chronic study. The extravasated erythrocytes fill many of the alveoli.

    Authors

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist/NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Darlene Dixon, DVM, PhD, DACVP
    Group Leader
    Molecular Pathogenesis Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Ronald A. Herbert, DVM, PhD
    Group Leader/NTP Pathologist
    Pathology Support Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Lauren M. Staska, DVM, PhD, DACVP
    Senior Pathologist
    WIL Research
    Hillsborough, NC

    Reviewers

    Gary A. Boorman, DVM, PhD, DACVP, DABT, DACLAM
    Pathologist
    Covance Laboratories, Inc.
    Chantilly, VA

    Robert C. Sills, DVM, PhD, FIATP
    Chief, Cellular and Molecular Pathology Branch
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC