Respiratory System

Lung - Keratinizing Cyst

    Narrative
    Lung - Keratinizing cyst in a male F344/N rat from a chronic study. There is a large cyst filled with keratin.
    Lung - Keratinizing cyst in a male F344/N rat from a chronic study. The epithelium of the cyst wall is well differentiated, with orderly maturation of the cells.
    Lung - Keratinizing cyst in a female F344/N rat from a chronic study. There is a large, keratin-filled cyst.
    Lung - Keratinizing cyst in a female F344/N rat from a chronic study (higher magnification Figure 3). The epithelium in the wall of the cyst is well differentiated, with orderly maturation of the cells.

    Authors

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist/NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Darlene Dixon, DVM, PhD, DACVP
    Group Leader
    Molecular Pathogenesis Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Ronald A. Herbert, DVM, PhD
    Group Leader/NTP Pathologist
    Pathology Support Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Lauren M. Staska, DVM, PhD, DACVP
    Senior Pathologist
    WIL Research
    Hillsborough, NC

    Reviewers

    Gary A. Boorman, DVM, PhD, DACVP, DABT, DACLAM
    Pathologist
    Covance Laboratories, Inc.
    Chantilly, VA

    Robert C. Sills, DVM, PhD, FIATP
    Chief, Cellular and Molecular Pathology Branch
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC