Respiratory System

Lung - Mineral

    Narrative
    Lung, Interstitium - Mineral in a male F344/N rat from a chronic study. Deeply basophilic material is present within the expanded alveolar septa.
    Lung, Interstitium - Mineral in a male F344/N rat from a chronic study. Basophilic mineral is present within cells and lining the alveolar septae.
    Lung, Interstitium - Mineral in a male F344/N rat from a chronic study. Many of the fragmented alveolar septae contain basophilic material.
    Lung, Interstitium - Mineral in a male F344/N rat from a chronic study (higher magnification of Figure 3). The mineral has been deposited primarily along basement membranes.

    Authors

    Mark F. Cesta, DVM, PhD, DACVP
    Staff Scientist/NTP Pathologist
    NTP Pathology Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Darlene Dixon, DVM, PhD, DACVP
    Group Leader
    Molecular Pathogenesis Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Ronald A. Herbert, DVM, PhD
    Group Leader/NTP Pathologist
    Pathology Support Group
    National Toxicology Program
    National Institute of Environmental Health Sciences
    Research Triangle Park, NC


    Lauren M. Staska, DVM, PhD, DACVP
    Senior Pathologist
    WIL Research
    Hillsborough, NC

    Reviewers

    Gary A. Boorman, DVM, PhD, DACVP, DABT, DACLAM
    Pathologist
    Covance Laboratories, Inc.
    Chantilly, VA

    Robert C. Sills, DVM, PhD, FIATP
    Chief, Cellular and Molecular Pathology Branch
    National Toxicology Program
    National Institute of Environmental Health Sciences, Research Triangle Park, NC